Discussions

iPSCs (induced pluripotent stem cells) that can differentiate into any cell type have emerged as an effective platform for the construction of disease models. iPSC-based disease models have been used for studying the pathological mechanisms of disease and discovering novel therapies. Compared to animal models and immortalized cell systems, iPSC-based disease models offer patient-specific, scalable biologic material of various tissue types and a complicated genetic signature of human tissue.