Discussions

The main limitation of cell-based therapies is the viability and function of transplanted cells. After cell transfer, therapeutic cells often rely on adjuvants, such as the simultaneous delivery of drugs. These adjuvants are designed to maximize the donor cell efficacy, phenotype and / or durability in vivo.

Here at Creative Biolabs, we developed a method via the conjugation of adjuvant–loaded nanoparticles to the surfaces of therapeutic cells to enhance cell therapy. This approach is a simple and generalizable strategy to augment cytoreagents while minimizing the systemic side effects of adjuvants.

Types of Conjugates

Peptide-loaded Nanoparticles
Antibody-loaded Nanoparticles
Drug-loaded Nanoparticles
Vaccine-loaded Nanoparticles
Nucleic Acids-loaded Nanoparticles
Fluorescent-loaded Nanoparticles

To provide best-in-class CALNP development services, Creative Biolabs brings together the most renowned cell engineering experts and long-term experience in cell surfce modification. Don't miss the opportunity to enter the clinic by working with service providers who provide the strongest cell therapy tools on the market!