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Epitope-specific Antibody Design

With our well-established epitope-specific antibody design platform, we are confident in providing unique epitope-specific antibodies with high specificity and affinity.

Due to their ability to bind certain molecules with high affinity and specificity, antibodies have become potent tools in life sciences research as well as in diagnostic and therapeutic applications. Generally, it is arduous and sometimes difficult to produce antibodies to target specific epitopes within a protein, especially when these epitopes are not effective antigens. Therefore, Creative Biolabs has established a more rational strategy for antibody design, which is a peer-reviewed protein engineering algorithm. It is based on natural mAb backbone conformations and sequences, which enable the design of human, highly developable, and stable epitope-specific mAbs. In general, our novel epitope-specific antibody design service mainly consists of Antibody Structure modeling, Antibody-antigen Complex Analysis, Computer-aided Affinity Maturation, Antibody Structure Determination, and Experimental Validation.