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For more than 15 years, BOC Sciences has been manufacturing oligonucleotides for pre-clinical, clinical, pharmaceutical, food safety, and animal health industries.

BOC Sciences' Manufacturing Capability

BOC Sciences has manufacturing facilities with GMP and ISO certifications. We can provide customized and flexible oligonucleotide GMP production services to meet different GMP-grade production needs. We exceed our customers' expectations by providing exceptional personalized solutions through reproducible systems that meet regulatory standards.

BOC Sciences,as one of the best GMP Oligonucleotide Manufacturing companies in the USA, provides the following:

Process development

Scale-up, scale-down & process transfer

Production capacity ranges from milligrams to hundreds of kilograms

State-of-the-art technology in oligonucleotide synthesis and downstream processing

Quality-controlled cGMP oligonucleotide laboratory

Purification and verification

Oligonucleotide Applications

Gene Therapy: Oligonucleotides are mainly involved in the process of RNA interference (RNAi) to achieve specific inhibition of the expression of target genes. Both small interfering RNA (siRNA) and microRNA (miRNA) are common RNAi tools.

Genomics Research: Oligonucleotides can be used in DNA sequencing technologies to accelerate in-depth development of the structure and function of genomes.

Gene Editing: Oligonucleotides play an important role in CRISPR/Cas9 gene editing by helping sgCas9 proteins to make specific gene modifications on target DNA via sgRNA.

Diagnostic Tool: Oligonucleotides can be used as molecular probes to detect specific genes or viral sequences, thus playing a role in medical diagnostics and disease monitoring.

Oligonucleotide Drug Development: The specific properties of oligonucleotide molecules can be used to intervene in disease onset and progression, usually by targeting disease-associated regulation of gene expression, protein function, or viral replication. Oligonucleotide drugs can be developed for the treatment of cancer, hereditary diseases, cardiovascular diseases, neurodegenerative diseases etc.

Advantages of Our GMP Oligos Services

High quality and Compliant Oligonucleotides: As GMP requires strict quality control and management, BOC Sciences ensures the delivery of high quality, pure and GMP compliant oligonucleotide products.

Experienced Team: BOC Sciences has a team of experienced and professional experts who are able to rationally plan the production process, maintain quality control throughout the process, and respond to potential problems in a timely manner.

A Trusted and Well-known Contract Manufacturing Partner: GMP certification is a strong competitive advantage in the marketplace for BOC Sciences' oligonucleotide products to gain customers' trust.

State of the Art Manufacturing Facilities: BOC Sciences has leading-edge production equipment, as well as a well-established system of environmental management and facility maintenance to ensure that the production environment is up to standard, thus guaranteeing the high purity of the oligonucleotide products.

Source:https://rna.bocsci.com/products-services/gmp-oligonucleotide-manufacturing-services.html