Discussions

single cell genomics​ is a fast growing subject that is shedding new light on a wide range of complex biological systems, from the diversity of the microbial ecosphere to the genomics of human cancer. By physically separating chromosomes to reduce the complexity of genomic signals, single-cell omics technology now offers a higher-resolution picture of the genomic content of specimens.

Genomic DNA can be used to profile the transcriptome and the proteome, whereas RNA from the same cell can be used to test the single-cell genome, methylome, or chromatin accessibility.