Discussions
Is it Safe to Drive with a Cracked Windshield?
Do I need enzyme stabilization & formulation as part of product development?
A: Enzyme formulation is one last and important step in commercializing an enzyme containing product. Nonetheless, the step has not yet received enough notice for its key role in effectively delivering the intended performance of the product. The main purpose of formulation is to preserve the enzyme in a ready-to-use form until consumed by the customer. Many companies spent a significant amount of resource and time on developing and testing the new enzyme product in details to deliver perfect biochemistry. However, final customers are only interested in the safety, stability, and aesthetics of the products on the shelf. Therefore, the product is only completed when it goes into the final package. At Creative Enzymes, we understand the importance of stable enzyme activity and will help you keep the enzymes stable during long-term storage. We also perform proper aging tests that predict the shelf life of an enzyme product using acceleration tests and kinetic models. In the end, we are happy to develop and optimize the product formulation for a specific enzyme.
Nanozyme-Based UV-Blocking Sunscreen
Ultraviolet (UV) radiation in sunlight is a complete carcinogen because it damages DNA, suppresses anti-tumor immunity, and promotes cancer metastasis. A simple and effective way to avoid harmful effects is to use sunscreen that protects against UV rays. However, currently used materials such as zinc oxide and titanium dioxide undergo photodegradation and produce reactive oxygen species (ROS), which may cause oxidative stress to tissues or damage DNA. Therefore, nanozymes have received a lot of attention as alternatives to natural enzymes.
What Are IV Drips and How Do They Work?
IV drips, or intravenous drips, are a medical treatmentin which fluids, medications, or nutrients are delivered directly into the bloodstream through a vein. They are typically administered using a small, flexible tube known as an IV catheter. IV drips are used for various purposes, such as rehydration, medication delivery, and nutrient supplementation.
Exosome Biotinylation
Investigating the functions of exosomes in therapeutic and diagnostic applications has received increasing focus. An innovative method for tracking exosome trafficking in vivo is called exosome labeling, and it helps to improve exosome-based diagnosis and therapy.
Exosomes are a type of extracellular vesicles that carry many components of their parent cells, including nucleic acids and proteins. They have a diameter of 30-150 nm. The use of exosome biotin labeling could be a very useful method for examining the biological characteristics of exosomes. By binding to streptavidin and avidin, biotin can be used to mark specific exosome proteins, allowing for the tracking of exosome trafficking.
IgM-Based Diagnosis
Human auto-antibody immunoglobulin M (IgM) has been shown to be a potent diagnostic tool for a variety of illnesses, including immune system disorders and malignancies. IgM has been extensively utilized to assess Epstein-Barr virus (EBV) infections in young children, according to recent investigations. In the meantime, a wide range of clinical investigations have been carried out utilizing alpha-fetoprotein (AFP)-IgM complexes, a significant biomarker that is frequently employed for HCC therapy, to diagnosis small hepatocellular carcinoma (HCC).
Together, you and our therapeutic antibody study-focused scientists will identify the best course of action and approach for your investigation. We can offer top-notch services for IgM-based diagnostics because to our highly skilled professionals and cutting-edge platforms.
Immunoprecipitation (IP)
The process of precipitating a protein antigen out of solution with an antibody that binds to that specific protein precisely is known as immunoprecipitation (IP). A specific protein can be separated and concentrated with this method from a sample that contains thousands of other proteins.
Lymph Cancer
Cancer can essentially emerge in the lymph nodes in two ways: either it originates there or it spreads there from another location. Lymphoma is the term for cancer that develops from the lymph nodes. A class of blood tumors known as lymphomas arises from lymphocytes, a subset of white blood cells. Enlargement of the lymph nodes, fever, intense sweats, weight loss, itching, and persistent fatigue are some of the possible symptoms. Most of the time, the swollen lymph nodes don't hurt. At night, the patients may sweat.
Immunoassay
The foundation of immunoassays is the idea that a given antigen will trigger an extremely focused (unique) immune response, and that target compounds can be found in a sample by using the proteins (called antibodies) that are generated as a result of the immunological reaction. Immunoassays are quick and precise diagnostic procedures that use various proteins and antibodies to monitor biological systems. Immunoassays are based on an antibody's capacity to attach to a particular molecular structure and can be employed in the lab to identify particular compounds.
Carboxyl-Terminal Peptide (CTP)
Previous research has shown that compared to other heterodimeric glycohormones including follicle-stimulating hormone (FSH), luteinizing hormone (LH), and thyroid-stimulating hormone (TSH), human chorionic gonadotropin (hCG) has a substantially longer half-life. The primary cause is the presence of a CTP in the hCG-subunit (HCG-) that has about 31 amino acids and forms four O-glycosylation sites that end in sialic acid residues. Monosaccharides with a negative charge are sialic acids. Recombinant therapeutic peptides or proteins will have delayed renal clearance and a longer half-life because negatively charged polysaccharides on the glomerular filter membrane will reject them.