Discussions
Discovery process of live biotherapeutics
Challenges and opportunities in live biotherapeutic products development
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Circulating Tumor Cells
Circulating tumor cells (CTCs) have been shown to exhibit a significant degree of cellular heterogeneity in single-cell omics data in recent years. This heterogeneity is indicative of both the possible tumor heterogeneity inside a single patient as well as between different individuals. The identification of heterologous resistance mechanisms in the treatment of refractory malignancies has been made possible by these investigations. The existence and degree of heterogeneity identified by the single-cell omics analysis of CTCs have significant clinical implications for comprehending and forecasting the emergence of therapeutic resistance in different types of solid tumors as well as for creating effective therapeutic approaches for the management of cancer treatments.
Isothermal Nucleic Acid Amplification
The isothermal process and high specificity of powerful and simple isothermal nucleic acid amplification make it a desirable technique for nucleic acid detection. Scientists at Creative Biolabs are able to build the most appropriate microfluidic chips to enable the realization of POC detection by combining isothermal nucleic acid amplification with microfluidic technology. This allows for the miniaturization of the isothermal nucleic acid amplification detection system. Microfluidic chips are available for all popular isothermal amplification technologies, such as but not restricted to:
BTN2A1 Antibody
This gene is a member of the butyrophilin protein family's BTN2 subfamily of genes, which encodes proteins. The gene is part of the growing B7/butyrophilin-like group, a subgroup of the immunoglobulin gene superfamily, and is found in a cluster on chromosome 6. The encoded protein plays a crucial role in the metabolism of lipids, fatty acids, and steroids as a B box protein in the plasma membrane.
Ribosome and Hepatocellular Cancer
Ribosome and Hepatocellular Cancer
Ribosomes are locations for the synthesis of proteins and feature intricate structures and a variety of uses. Comprising distinct ribosomal proteins (RPs) and ribosomal RNAs (rRNAs), ribosomes play a crucial role in numerous biological processes within cells. Moreover, rRNA and RPs, their main constituents, are intimately linked to a range of human illnesses, including cancer and hematologic disorders. The role and function of ribosomes in the formation of cancer is currently the focus of scientific research on the pathology of tumor development.
Disease Therapy
Humoral immunity is mostly dependent on highly specialized, naturally occurring molecules called antibodies. They are the primary means by which the immune system identifies, neutralizes, or gets rid of invading organisms such as bacteria, viruses, fungi, and parasites. Since the late 19th century, antibodies have been employed as medicines to treat infectious disorders in the form of patient- or animal-derived sera. Since the 1970s, when monoclonal antibodies (mAbs) were developed, the concept of antibody therapy—which targets tumor-specific antigens—has drawn more attention than just infectious disorders.