Discussions
Exosome Biotinylation
Investigating the functions of exosomes in therapeutic and diagnostic applications has received increasing focus. An innovative method for tracking exosome trafficking in vivo is called exosome labeling, and it helps to improve exosome-based diagnosis and therapy.
Exosomes are a type of extracellular vesicles that carry many components of their parent cells, including nucleic acids and proteins. They have a diameter of 30-150 nm. The use of exosome biotin labeling could be a very useful method for examining the biological characteristics of exosomes. By binding to streptavidin and avidin, biotin can be used to mark specific exosome proteins, allowing for the tracking of exosome trafficking.
IgM-Based Diagnosis
Human auto-antibody immunoglobulin M (IgM) has been shown to be a potent diagnostic tool for a variety of illnesses, including immune system disorders and malignancies. IgM has been extensively utilized to assess Epstein-Barr virus (EBV) infections in young children, according to recent investigations. In the meantime, a wide range of clinical investigations have been carried out utilizing alpha-fetoprotein (AFP)-IgM complexes, a significant biomarker that is frequently employed for HCC therapy, to diagnosis small hepatocellular carcinoma (HCC).
Together, you and our therapeutic antibody study-focused scientists will identify the best course of action and approach for your investigation. We can offer top-notch services for IgM-based diagnostics because to our highly skilled professionals and cutting-edge platforms.
Immunoprecipitation (IP)
The process of precipitating a protein antigen out of solution with an antibody that binds to that specific protein precisely is known as immunoprecipitation (IP). A specific protein can be separated and concentrated with this method from a sample that contains thousands of other proteins.
Lymph Cancer
Cancer can essentially emerge in the lymph nodes in two ways: either it originates there or it spreads there from another location. Lymphoma is the term for cancer that develops from the lymph nodes. A class of blood tumors known as lymphomas arises from lymphocytes, a subset of white blood cells. Enlargement of the lymph nodes, fever, intense sweats, weight loss, itching, and persistent fatigue are some of the possible symptoms. Most of the time, the swollen lymph nodes don't hurt. At night, the patients may sweat.
Immunoassay
The foundation of immunoassays is the idea that a given antigen will trigger an extremely focused (unique) immune response, and that target compounds can be found in a sample by using the proteins (called antibodies) that are generated as a result of the immunological reaction. Immunoassays are quick and precise diagnostic procedures that use various proteins and antibodies to monitor biological systems. Immunoassays are based on an antibody's capacity to attach to a particular molecular structure and can be employed in the lab to identify particular compounds.
Carboxyl-Terminal Peptide (CTP)
Previous research has shown that compared to other heterodimeric glycohormones including follicle-stimulating hormone (FSH), luteinizing hormone (LH), and thyroid-stimulating hormone (TSH), human chorionic gonadotropin (hCG) has a substantially longer half-life. The primary cause is the presence of a CTP in the hCG-subunit (HCG-) that has about 31 amino acids and forms four O-glycosylation sites that end in sialic acid residues. Monosaccharides with a negative charge are sialic acids. Recombinant therapeutic peptides or proteins will have delayed renal clearance and a longer half-life because negatively charged polysaccharides on the glomerular filter membrane will reject them.
Guanosine Analogue
A deeper comprehension of the coronavirus life cycle has led to the identification and confirmation of numerous targets for therapeutic intervention as well as an expansion of the classes of antiviral medications.
Guanosine Analogue
A deeper comprehension of the coronavirus life cycle has led to the identification and confirmation of numerous targets for therapeutic intervention as well as an expansion of the classes of antiviral medications.
Western Blotting Analysis
Western blotting (WB), in conjunction with polyacrylamide gel electrophoresis, is a crucial analytical method and instrument in biological sciences. It is still used as a potent diagnostic strategy in medical labs. However, its process involves a number of phases that are typically time and resource consuming in addition to having low throughput.